When Depression Won’t Lift, Spravato® May Offer a New Path Forward
If you have tried antidepressant after antidepressant and still feel stuck, you are not out of options. RayMex Wellness offers REMS-certified Spravato® (esketamine) for treatment-resistant depression — in person in Stoughton, Massachusetts.
Spravato® (esketamine) is an FDA-approved nasal spray for treatment-resistant depression, given in a certified medical office under supervision. At RayMex Wellness in Stoughton, MA, our REMS-certified team provides Spravato alongside medication management and therapy. Most insurance is accepted — take our quick screening below or call (617) 419-0482.
Living with depression that will not respond to treatment is exhausting. You have done everything right — taken the medications, gone to the appointments, tried to hold on — and yet the heaviness stays. We want you to know that feeling is real, and it is not the end of your story.
Spravato® (esketamine) works differently from traditional antidepressants. Instead of targeting serotonin, it acts on glutamate, a brain chemical that helps rebuild connections between brain cells. For many people who have not responded to two or more antidepressants, this new pathway can bring relief.
At RayMex Wellness, Spravato is never given alone. We combine it with careful medication management, therapy, and steady human support so you are cared for as a whole person.
You May Be a Candidate If You Experience
How Spravato Works at RayMex Wellness
Why Choose RayMex Wellness
Who We Help
Adults with treatment-resistant depression (depression that has not improved after two or more antidepressants), and adults with major depressive disorder experiencing active suicidal thoughts. Every candidate is carefully evaluated first to make sure Spravato is safe and appropriate.
Office Location
Visit us at 11 Freeman St, Suite 8, Stoughton, MA 02072. Both in-person and telehealth appointments available.
What Spravato May Cost With Insurance
Costs vary by plan, deductible, and eligibility. These figures are estimates only and are not a guarantee of price or coverage. Our team will verify your specific benefits and explain your expected out-of-pocket cost before you begin.
Frequently Asked Questions
What is Spravato and how does it work?
Spravato® is the brand name for esketamine, an FDA-approved nasal spray for treatment-resistant depression. Unlike traditional antidepressants that work on serotonin, Spravato acts on glutamate, a brain chemical involved in mood and the connections between brain cells. It is taken in a certified medical office, where you are monitored for about two hours after each dose.
Who qualifies for Spravato treatment?
Spravato is approved for adults with treatment-resistant depression — depression that has not improved after at least two different antidepressants — and for adults with major depressive disorder who have active suicidal thoughts. Every person starts with a full psychiatric evaluation so we can confirm it is safe and appropriate.
Does insurance cover Spravato in Massachusetts?
Most commercial insurance plans in Massachusetts cover Spravato for treatment-resistant depression, and many patients pay only a small copay per session. Coverage under Medicare and MassHealth varies. We verify your specific benefits before you begin. Costs are estimates and not guaranteed.
How long is a Spravato session and how often do I come in?
Plan for about two hours per visit. You self-administer the nasal spray under supervision, then rest while we monitor you. In the first few weeks, sessions are usually twice a week, then space out gradually as you stabilize. You will need someone to drive you home.
Is Spravato the same as ketamine?
They are related but not the same. Spravato (esketamine) is a specific, FDA-approved form delivered as a nasal spray and regulated under a federal safety program called REMS. Because it is FDA-approved and REMS-certified, it follows strict safety monitoring and is more commonly covered by insurance than off-label ketamine.
In crisis or need urgent help? If you or someone you love is in danger, call or text 988 (Suicide & Crisis Lifeline), available 24/7, or dial 911.
Ready to Take the Next Step?
Take the quick screening below, book an appointment, or call us today. Spravato is provided in person in Stoughton, MA.
Results vary. RayMex Wellness does not guarantee specific treatment outcomes. All care is individualized. This page is for educational purposes and is not a substitute for professional medical advice, diagnosis, or treatment.
Am I a Candidate for Spravato®?
Answer a few confidential questions to see if Spravato may be a fit. When you finish, you can book your consultation right from your results.
Is Spravato Right for You?
Answer a few quick questions to see if you may be a candidate for Spravato treatment. This takes about 2 minutes and is completely confidential. This is a screening tool only — not a diagnosis.
This screening tool is for informational purposes only and does not constitute a medical diagnosis. Only a licensed provider can determine actual eligibility for Spravato treatment following a comprehensive evaluation.