Spravato® Treatment in Stoughton, MA
FDA-approved Spravato® (esketamine) nasal spray for treatment-resistant depression, provided in our REMS-certified Stoughton office under medical supervision. Most insurance accepted.
11 Freeman St, Suite 8, Stoughton, MA 02072
Spravato® (esketamine) is an FDA-approved nasal spray for treatment-resistant depression, administered in our REMS-certified Stoughton, MA office under medical supervision. Most insurance accepted. Call 617-419-0482 or take the free screening below to see if you’re a candidate.
Spravato Treatment Stoughton MA
When depression hasn’t improved after trying multiple antidepressants, Spravato® offers a different, evidence-based path forward. At RayMex Wellness in Stoughton, Massachusetts, our REMS-certified team provides esketamine treatment in a calm, supervised setting — fully integrated with your medication management and therapy.
Learn more about how esketamine works on our Spravato for depression care page, or book an appointment to get started.
Who Is a Candidate?
What to Expect During Treatment
Evaluation & Screening
A comprehensive psychiatric evaluation confirms whether Spravato is appropriate and coordinates it with your overall treatment plan.
In-Office Administration
You self-administer the esketamine nasal spray in our calm, private treatment room under direct medical supervision.
2-Hour Monitoring
After each dose you are monitored for at least two hours for blood pressure, sedation, and any side effects before heading home.
Ongoing Care
We track your progress, adjust the schedule, and continue medication management and therapy for lasting results.
REMS Safety Protocol
Spravato is only available through a restricted federal safety program called REMS (Risk Evaluation and Mitigation Strategy). It cannot be dispensed to take home — every dose is self-administered in a REMS-certified medical office and followed by supervised monitoring.
- Administered only in our REMS-certified Stoughton, MA office
- Continuous monitoring by a medical professional for at least 2 hours after each dose
- Blood pressure and sedation checks before you are cleared to leave
- You must arrange a ride home — no driving until the next day after restful sleep
Insurance Coverage
Most major plans cover Spravato when medical criteria are met. Our team verifies your benefits and handles prior authorization before treatment begins. Accepted plans include:
Spravato vs. Oral Antidepressants vs. TMS
Spravato (esketamine) works differently from traditional antidepressants and TMS. Here is how the most common treatment-resistant depression options compare on mechanism, onset, administration, and insurance.
| Treatment | Mechanism | Onset | Administration | Insurance |
|---|---|---|---|---|
| Spravato (Esketamine) | NMDA Receptor Antagonist | 24-48 hours | In-office nasal spray (2-hr REMS observation) | BCBS, Medicare, MassHealth, Aetna |
| Oral Antidepressants (SSRIs) | Serotonin Reuptake Inhibition | 4-8 weeks | Daily oral pill at home | Standard coverage |
| TMS | Electromagnetic Brain Stimulation | 2-4 weeks | In-office daily (5 days/wk for 6 wks) | Widely covered (prior auth) |
Insurance coverage varies by plan. Our team verifies your benefits before treatment begins.
Am I a Candidate for Spravato®?
Answer a few confidential questions to see if Spravato may be a fit. When you finish, you can book your consultation right from your results.
Is Spravato Right for You?
Answer a few quick questions to see if you may be a candidate for Spravato treatment. This takes about 2 minutes and is completely confidential. This is a screening tool only — not a diagnosis.
This screening tool is for informational purposes only and does not constitute a medical diagnosis. Only a licensed provider can determine actual eligibility for Spravato treatment following a comprehensive evaluation.
Frequently Asked Questions
What is Spravato® (esketamine)?
Spravato® is an FDA-approved nasal spray containing esketamine. It is prescribed for treatment-resistant depression (depression that has not responded to at least two oral antidepressants) and for depressive symptoms in adults with major depressive disorder who have suicidal thoughts or behavior. It is always given in a certified medical setting under supervision.
Am I a candidate for Spravato treatment in Stoughton, MA?
You may be a candidate if you are an adult with major depressive disorder or treatment-resistant depression and have tried other antidepressants without adequate relief. A provider evaluation confirms candidacy. Take our free 2-minute screening below or call (617) 419-0482 to find out.
Is Spravato covered by insurance?
Most major plans cover Spravato when medical criteria are met. RayMex Wellness accepts MassHealth, Medicare, Blue Cross Blue Shield of Massachusetts, Tufts Health Plan, Harvard Pilgrim, and more. Our team helps verify your benefits and obtain any prior authorization before treatment.
What is the REMS safety program?
Spravato is only available through a restricted program called REMS (Risk Evaluation and Mitigation Strategy). It must be administered in a REMS-certified healthcare setting where you are monitored by a medical professional for at least two hours after each dose. RayMex Wellness is a REMS-certified provider in Stoughton, MA.
How long does a Spravato appointment take?
Plan for about 2 to 2.5 hours per visit. You self-administer the nasal spray under supervision, then remain in the office for a monitoring period of at least two hours. Because Spravato can cause drowsiness and dizziness, you must arrange a ride home and cannot drive until the next day after restful sleep.
How often will I need treatment?
A typical course begins with twice-weekly sessions for the first four weeks, followed by weekly and then every-other-week maintenance sessions based on your response. Your provider personalizes the schedule and continues your other depression care alongside Spravato.
Ready to Take the Next Step?
Book an appointment or call us today. Spravato® is provided in person at our REMS-certified office in Stoughton, MA.
Individual results vary, and no specific treatment outcome is guaranteed. Spravato® (esketamine) is a prescription medication that is prescribed only when it is clinically appropriate, following a psychiatric evaluation and in accordance with the FDA REMS program. Not everyone is a candidate. Benefits, risks, and side effects differ from person to person, and eligibility and treatment decisions are always made together with your provider based on your individual clinical picture. This information is educational and is not a substitute for professional medical advice.
Clinically Reviewed by:
Nnemeka Okpala, PMHNP-BC, APRN
RayMex Wellness LLC
Last Updated: August 2026